Abstract: The aim of this study was to investigate what attitudes do District Nurses have towards people with AIDS and what knowledge do they have of AIDS. It is hoped that the results will help indicate the direction of future inservice education.102 District Nurses were given a questionnaire that examined knowledge and attitudes, using both Yes/No responses, and a five point likert scale.The results show that there is a relationship between knowledge and attitudes (p=3.8%). Attitudes were generally more positive than knowledge. The study indicated that attitudes deteriorated with increasing age whereas they improved with increasing experience. For those who claimed to have had little or no education the study showed a relationship between lower knowledge and poorer attitudes. The study showed that further education is needed in areas such as: transmission of HIV, care involved for people with AIDS, resources available and the issues surrounding this disease